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The COVID-19 Pandemic
04/04/2020 @ 10:00 AM - 11:00 AM PDT
Free
This presentation has since taken place, you can view the film recording here
The COVID-19 Pandemic
Robert A. Hendrix, M.D.
A major pandemic is sweeping the globe. Cases of COVID-19 are growing exponentially as people spread the disease throughout our connected world. Individuals and societal groups are reacting differently, looking for solutions to stem the threat to our health and way of life.
Dr. Hendrix will talk about what we all want to know – what this is, what you can do about it, and what medical researchers are doing to try to find ways to combat the virus.
Specifics of Dr. Hendrix’s presentation:
— SARS-CoV-2 detection: basic molecular biology of the coronavirus, emphasizing detection targets of diagnostic tests for gene fragments using reverse transcriptase / polymerase chain reaction (PCR) techniques or antibody tests to detect convalescent states following initial infection
— COVID-19 (coronavirus disease): pathophysiology of cytokine explosion and acute respiratory distress syndrome (ARDS) and limitations of cytokine inhibitors
— Individual actions: strategies for avoidance and containment
— Potential treatments under evaluation:
> “borrowed” multi-drug regimens (drug re-positioning strategies) from other viral management protocols
> novel “off-schedule” application of drugs such as hydroxychloroquine (Plaquenil), a synthetic derivative of quinine, the first drug used effectively to treat malaria
> infusion of humoral antibodies (passive immunity) or inducing active immunity by vaccines targeting the Spike S-protein or capsid proteins
> pharmaceutical agents that target viral enzymes such as protease and RNA-replicase (potential “designer drugs”)
> Angiotensin Converting Enzyme (ACE)-II inhibitors to block virion access to cellular receptors
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